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Author (up) Brunes, A.; Augestad, L.B.; Gudmundsdottir, S.L. url  doi
  Title Personality, physical activity, and symptoms of anxiety and depression: the HUNT study Type Journal Article
  Year 2013 Publication Social Psychiatry and Psychiatric Epidemiology Abbreviated Journal Soc Psychiatry Psychiatr Epidemiol  
  Volume 48 Issue 5 Pages 745-756  
  Keywords  
  Abstract PURPOSE: To analyze the association between physical activity (PA), symptoms of depression and anxiety, and personality traits. METHODS: Cross-sectional study from a Norwegian population-based survey conducted in the period 2006-2008. The sample consisted of a total of 38,743 subjects aged >/= 19 years, 56.1 % women and 43.9 % men. Demographic variables, PA, depression and anxiety (The Hospital Anxiety and Depression Scale), and personality (Eysenck Personality Questionnaire) were assessed by self-reporting measurements. RESULTS: Individuals who reported moderate and high PA had significantly lower scores on depression and anxiety compared with less physically active individuals (p < 0.05). Significantly lower risk of HADS-defined depression and anxiety was associated with frequency, duration, and intensity of activity among women (p < 0.05), and significantly lower risk of HADS-defined depression was associated with frequency, duration, and intensity of activity among men (p < 0.05). There was a significant linear trend between extroversion and levels of PA (p < 0.01) and between neuroticism and PA (p < 0.01). CONCLUSIONS: Subjects reporting regular leisure-time PA were less likely to report symptoms of HADS-defined depression and anxiety. Personality may be an underlying factor in explaining this association.  
  Address Faculty of Social Sciences and Technology Management, Department of Human Movement Science, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway. audun.brunes@ntnu.no  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0933-7954 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23052425 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1460  
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Author (up) Brunes, A.; Flanders, W.D.; Augestad, L.B. url  doi
  Title Self-reported visual impairment, physical activity and all-cause mortality: The HUNT Study Type Journal Article
  Year 2017 Publication Scandinavian Journal of Public Health Abbreviated Journal Scand J Public Health  
  Volume 45 Issue 1 Pages 33-41  
  Keywords Aged; Aged, 80 and over; *Cause of Death; *Exercise; Female; Humans; Male; Middle Aged; Norway/epidemiology; Proportional Hazards Models; Prospective Studies; Risk Assessment; *Self Report; Vision Disorders/*epidemiology; *All-cause mortality; *HUNT study; *physical activity; *prospective cohort study; *self-reported; *visual impairment  
  Abstract AIMS: To examine the associations of self-reported visual impairment and physical activity (PA) with all-cause mortality. METHODS: This prospective cohort study included 65,236 Norwegians aged 20 years who had participated in the Nord-Trondelag Health Study (HUNT2, 1995-1997). Of these participants, 11,074 (17.0%) had self-reported visual impairment (SRVI). The participants' data were linked to Norway's Cause of Death Registry and followed throughout 2012. Hazard ratios and 95% confidence intervals (CI) were assessed using Cox regression analyses with age as the time-scale. The Cox models were fitted for restricted age groups (<60, 60-84, 85 years). RESULTS: After a mean follow-up of 14.5 years, 13,549 deaths were identified. Compared with adults with self-reported no visual impairment, the multivariable hazard ratios among adults with SRVI were 2.47 (95% CI 1.94-3.13) in those aged <60 years, 1.22 (95% CI 1.13-1.33) in those aged 60-84 years and 1.05 (95% CI 0.96-1.15) in those aged 85 years. The strength of the associations remained similar or stronger after additionally controlling for PA. When examining the joint associations, the all-cause mortality risk of SRVI was higher for those who reported no PA than for those who reported weekly hours of PA. We found a large, positive departure from additivity in adults aged <60 years, whereas the departure from additivity was small for the other age groups. CONCLUSIONS: Adults with SRVI reporting no PA were associated with an increased all-cause mortality risk. The associations attenuated with age.  
  Address 4 Department of Visual Impairment, Statped Mid-Norway, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1403-4948 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27913690 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1893  
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Author (up) Brunes, A.; Gudmundsdottir, S.L.; Augestad, L.B.   
  Title Gender-specific associations between leisure-time physical activity and symptoms of anxiety: the HUNT study Type Journal Article
  Year 2015 Publication Soc Psychiatry Psychiatr Epidemiol Abbreviated Journal Social psychiatry and psychiatric epidemiology  
  Volume 50 Issue 3 Pages 419-427  
  Keywords Adult; Aged; Aged, 80 and over; Anxiety/*diagnosis/epidemiology/psychology; Anxiety Disorders/*diagnosis/psychology; Exercise/*psychology; Female; Humans; Incidence; Leisure Activities/*psychology; Male; Middle Aged; Norway; Prospective Studies; Sex Factors; Surveys and Questionnaires; Young Adult; HUNT2; HUNT3  
  Abstract PURPOSE: The underlying goal of the study was to examine gender-specific effects of leisure-time physical activity on the development of symptoms of anxiety. METHODS: The second wave of a prospective cohort survey (HUNT 2) was conducted during 1995-1997 in the county of Nord-Trondelag, Norway, with a follow-up in 2006-2008 (HUNT 3). The sample consisted of 12,796 women and 11,195 men with an age range of 19-85 years. A binomial model with a log-link function and generalized linear model analysis with gamma distribution was used to assess the association between physical activity and anxiety symptoms (Hospital Anxiety and Depression Scale anxiety subscale, HADS-A). RESULTS: A total of 1,211 (9.5 %) women and 650 (5.8 %) men developed HADS-defined anxiety (>/=8 on the HADS-A scale). Men who scored in the middle tertile of the calculated physical activity index developed significantly fewer cases of HADS-defined anxiety compared with men in the lowest tertile (p  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Department of Neuroscience, The Faculty of Medicine, Norwegian University of Science and Technology Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number HUNT @ maria.stuifbergen @ Brunes2015 Serial 1797  
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Author (up) Brunes, A.; Gudmundsdottir, S.L.; Augestad, L.B. url  doi
  Title Gender-specific associations between leisure-time physical activity and symptoms of anxiety: the HUNT study Type Journal Article
  Year 2014 Publication Social Psychiatry and Psychiatric Epidemiology Abbreviated Journal Soc Psychiatry Psychiatr Epidemiol  
  Volume Issue Pages  
  Keywords HUNT2; HUNT3  
  Abstract PURPOSE: The underlying goal of the study was to examine gender-specific effects of leisure-time physical activity on the development of symptoms of anxiety. METHODS: The second wave of a prospective cohort survey (HUNT 2) was conducted during 1995-1997 in the county of Nord-Trondelag, Norway, with a follow-up in 2006-2008 (HUNT 3). The sample consisted of 12,796 women and 11,195 men with an age range of 19-85 years. A binomial model with a log-link function and generalized linear model analysis with gamma distribution was used to assess the association between physical activity and anxiety symptoms (Hospital Anxiety and Depression Scale anxiety subscale, HADS-A). RESULTS: A total of 1,211 (9.5 %) women and 650 (5.8 %) men developed HADS-defined anxiety (>/=8 on the HADS-A scale). Men who scored in the middle tertile of the calculated physical activity index developed significantly fewer cases of HADS-defined anxiety compared with men in the lowest tertile (p < 0.05). In the gamma regression analysis for women, having higher scores on the moderate-high physical activity was associated with fewer symptoms of anxiety (p < 0.01). CONCLUSIONS: Women developed almost twice as many cases of HADS-defined anxiety compared to men. Significant associations were found between general leisure-time physical activity and anxiety symptoms among women and men, but the true effect is likely to be different from the observed associations due to several threats to the internal validity in the study.  
  Address Department of Neuroscience, The Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0933-7954 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:24970575 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1638  
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Author (up) Gudmundsdottir, S.L.; Flanders, W.D.; Augestad, L.B. url  doi
  Title Menstrual Cycle Abnormalities in Healthy Women With Low Physical Activity: The North-Trondelag Population-based Health Study Type Journal Article
  Year 2014 Publication Journal of Physical Activity & Health Abbreviated Journal J Phys Act Health  
  Volume 11 Issue 6 Pages 1133-1140  
  Keywords HUNT1; HUNT2  
  Abstract BACKGROUND: Menstrual dysfunctions are often found in athletic women. This study evaluated the association between leisure time physical activity (LTPA) and menstrual function in healthy nonathletic women. METHODS: During 1984-1986, a population-based health survey (HUNT 1) was conducted in Nord-Trondelag, Norway, with follow-up (HUNT 2) in 1995-1997. Women < 45 years old in HUNT 2 were included in the current study. LTPA was assessed by questionnaire in HUNT 1 and HUNT 2, and menstrual function by questionnaire in HUNT 2. RESULTS: Adjusted odds ratios (OR's) for long cycles were increased in women who reported < 1 hour of light LTPA (OR = 1.4, 95% CI = 1.0-2.0) and 1-2 hours (OR = 1.3, 95% CI = 1.0-1.8) per week compared with women with >/= 3 hours/week. Adjusted OR for irregular cycles was decreased in women constantly in the lowest tertile of LTPA index in HUNT 1 and HUNT 2 (OR = 0.4, 95% CI = 0.2-0.9). Adjusted OR for prolonged bleeding was 2.6 (95% CI = 1.3-5.4) for women with < 1 hour/week of light LTPA and 2.3 (95% CI = 1.3-4.3) for women with 1-2 hours, compared with >/= 3 hours/week. CONCLUSIONS: Very low physical activity may increase the risk of menstrual cycle disruptions. Moderate PA should be encouraged for optimum reproductive health.  
  Address Dept of Human Movement Science, Norwegian University of Science and Technology, Trondheim, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1543-3080 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:25368942 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1641  
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Author (up) Gudmundsdottir, S.L.; Flanders, W.D.; Augestad, L.B. url  doi
  Title Physical activity and cardiovascular risk factors at menopause: the Nord-Trondelag health study Type Journal Article
  Year 2013 Publication Climacteric : the Journal of the International Menopause Society Abbreviated Journal Climacteric  
  Volume 16 Issue 4 Pages 438-446  
  Keywords Adult; Blood Glucose/analysis; Blood Pressure; Body Mass Index; Body Weight; Cardiovascular Diseases/*epidemiology; Cholesterol, HDL/blood; *Exercise; Female; Follow-Up Studies; Health Surveys; Humans; *Menopause; Metabolic Diseases/epidemiology; Middle Aged; Norway/epidemiology; Premenopause/physiology; Questionnaires; Risk Factors; Triglycerides/blood; Waist-Hip Ratio  
  Abstract BACKGROUND: Lowered physical activity levels may partially explain changes in metabolic risk factors in women after menopause. OBJECTIVES: To evaluate the association between physical activity and metabolic risk factors at baseline and after 11 years, as well as the change in that association over time in women who were premenopausal and >/= 40 years at baseline. METHODS: Subjects in a Norwegian population-based health survey answered questionnaires and had body and serum measurements during 1995-1997 (HUNT 2) and in a follow-up study during 2006-2008 (HUNT 3). Repeated-measures analyses were used to estimate the association between physical activity and metabolic factors, adjusting for age, smoking status, education, alcohol intake, and parity. Adjustment for hormonal treatment and medication was made, as appropriate. RESULTS: In women remaining premenopausal, a higher physical activity score in HUNT 3 was associated with lower weight (p < 0.01) and waist-hip ratio (p < 0.01) and higher high density lipoprotein (HDL) cholesterol in HUNT 3 (p < 0.01). In women that were postmenopausal by the time of follow-up, a higher physical activity score in HUNT 3 was associated with lower weight (p < 0.01), waist-hip ratio (p < 0.01), triglycerides (p < 0.01), and higher total cholesterol (p < 0.05), HDL cholesterol (p < 0.01), and diastolic blood pressure (p < 0.05) in HUNT 3. The association of total physical activity score with weight and waist-hip ratio was stronger in HUNT 3 than in HUNT 2 (p < 0.01). CONCLUSION: Increased physical activity may reduce the risk of adverse outcomes and use of pharmacological management in women of menopausal age.  
  Address Department of Human Movement Science, Norwegian University of Science and Technology, Trondheim, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1369-7137 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23347190 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1450  
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Author (up) Gudmundsdottir, S.L.; Flanders, W.D.; Augestad, L.B. url  doi
  Title Physical activity and age at menopause: the Nord-Trondelag population-based health study Type Journal Article
  Year 2013 Publication Climacteric : the Journal of the International Menopause Society Abbreviated Journal Climacteric  
  Volume 16 Issue 1 Pages 78-87  
  Keywords Adult; Age Factors; Confidence Intervals; Female; Health Surveys; Humans; Kaplan-Meier Estimate; Logistic Models; *Menopause; Middle Aged; Motor Activity/*physiology; Norway; Odds Ratio; Proportional Hazards Models; Young Adult  
  Abstract BACKGROUND: Age at menopause may affect women's subsequent morbidity and mortality. In contrast to numerous other health outcomes, little is known about the possible effects of physical activity on age at menopause. OBJECTIVES: To assess the relationship between leisure-time physical activity and age at menopause. METHODS: Premenopausal women participating in a population-based health survey (HUNT 2) conducted in the county of Nord-Trondelag, Norway reported their physical activity in the period of 1995-1997. Age at menopause was reported during 2006-2008 (HUNT 3). Cox proportional hazards models were used to estimate hazard ratios for menopause and logistic regression to estimate odds ratios for early menopause, with 95% confidence intervals, adjusting for age at menarche, parity, use of oral contraceptives prior to the 6 months preceding participation in HUNT 2, symptoms of depression, smoking status, and education. RESULTS: Women aged 40-49 years at baseline had lower hazard ratios for menopause when participating in any light leisure-time physical activity compared with no activity (p < 0.05) and similar results were observed in 19-39-year-olds. In 50-59-year-old women, the results varied greatly and did not reach statistical significance. CONCLUSIONS: The effects of leisure-time physical activity on age at menopause may be age-dependent. We found indications of earlier menopause for the least active women aged 19-49 years at baseline.  
  Address Department of Human Movement Science, Faculty of Social Sciences and Technology Management, Norwegian University of Science and Technology, Trondheim, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1369-7137 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:22339441 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1449  
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Author (up) Moe, B.; Augestad, L.B.; Flanders, W.D.; Dalen, H.; Nilsen, T.I.L. url  doi
  Title The adverse association of diabetes with risk of first acute myocardial infarction is modified by physical activity and body mass index: prospective data from the HUNT Study, Norway Type Journal Article
  Year 2014 Publication Diabetologia Abbreviated Journal Diabetologia  
  Volume Issue Pages  
  Keywords HUNT2  
  Abstract AIMS/HYPOTHESIS: Diabetes increases the risk of acute myocardial infarction (AMI) and effective means for primary prevention are warranted. We prospectively examined the joint association of diabetes and leisure-time physical activity, as well as of diabetes and BMI, with the risk of AMI. METHODS: A total of 55,534 men and women in the Norwegian HUNT Study were followed-up for first AMI by hospital admission registries and the Cause of Death Registry. Cox proportional adjusted HRs with 95% CIs were estimated. RESULTS: Overall, 1,887 incident AMIs occurred during 12.3 years. Compared with inactive people without diabetes, inactive people with diabetes had an HR of 2.37 (95% CI 1.58, 3.57), whereas the HR among highly active persons with diabetes was 1.04 (95% CI 0.62, 1.74). Normal-weight (BMI 18.5-25 kg/m2) persons with diabetes had an HR of 1.60 (95% CI 1.05, 2.44) and obese (BMI > 30 kg/m2) persons with diabetes had an HR of 2.55 (95% CI 1.97, 3.29) compared with normal-weight persons without diabetes. The data suggest biological interaction between diabetes and physical activity, with a relative excess risk of inactivity and diabetes of 1.43 (95% CI 0.08, 2.78). For obesity and diabetes, the excess risk due to interaction was smaller (0.67; 95% CI -0.24, 1.58). CONCLUSIONS/INTERPRETATION: Body weight and, in particular, physical activity modified the association between diabetes and risk of first AMI. This highlights the potential importance of physical activity and weight maintenance in primary prevention of AMI among people with diabetes.  
  Address Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, 7491, Trondheim, Norway, borge.moe@ntnu.no  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0012-186X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:25297571 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1654  
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Author (up) Moe, B.; Augestad, L.B.; Nilsen, T.I.L. url  doi
  Title Diabetes severity and the role of leisure time physical exercise on cardiovascular mortality: the Nord-Trondelag Health study (HUNT), Norway Type Journal Article
  Year 2013 Publication Cardiovascular Diabetology Abbreviated Journal Cardiovasc Diabetol  
  Volume 12 Issue Pages 83  
  Keywords Adult; Aged; Cardiovascular Diseases/complications/*mortality; Cohort Studies; *Diabetes Complications; *Diabetes Mellitus; *Exercise; Female; Humans; Leisure Activities; Male; Middle Aged; Norway/epidemiology; Proportional Hazards Models; Registries; Severity of Illness Index  
  Abstract BACKGROUND: Physical activity has been associated with lower cardiovascular mortality in people with diabetes, but how diabetes severity influence this association has not been extensively studied. METHODS: We prospectively examined the joint association of diabetes severity, measured as medical treatment status and disease duration, and physical exercise with cardiovascular mortality. A total of 56,170 people were followed up for 24 years through the Norwegian Cause of Death Registry. Cox proportional adjusted hazard ratios (HRs) with 95% confidence intervals (CI) were estimated. RESULTS: Overall, 7,723 people died from cardiovascular disease during the follow-up. Compared to the reference group of inactive people without diabetes, people with diabetes who reported no medical treatment had a hazard ratio (HR) of 1.65 (95% CI: 1.34, 2.03) if they were inactive and a HR of 0.99 (95% CI: 0.68, 1.45) if they reported >/=2.0 hours physical exercise per week. Among people who received oral hypoglycemic drugs or insulin, the corresponding comparison gave HRs of 2.46 (95% CI: 2.08-2.92) and 1.58 (95% CI: 1.21, 2.05), respectively. CONCLUSIONS: The data suggest a more favourable effect of exercise in people with diabetes who used medication than in those who did not, suggesting that physical exercise should be encouraged as a therapeutic measure additional to medical treatment.  
  Address Department of Human Movement Science, Norwegian University of Science and Technology, Trondheim, Norway. borge.moe@ntnu.no  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1475-2840 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23738538; PMC3680183 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1421  
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