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Author (up) Engdahl, B.; Krog, N.H.; Kvestad, E.; Hoffman, H.J.; Tambs, K. url  doi
  Title Occupation and the risk of bothersome tinnitus: results from a prospective cohort study (HUNT) Type Journal Article
  Year 2012 Publication BMJ Open Abbreviated Journal BMJ Open  
  Volume 2 Issue 1 Pages e000512  
  Keywords  
  Abstract Objectives Estimates of occupation-specific tinnitus prevalence may help identify high-risk occupations where interventions are warranted. The authors studied the effect of occupation on prevalence of bothersome tinnitus and estimated the attributable fraction due to occupation. The authors also studied how much of the effect remained after adjusting for noise exposure, education income, hearing thresholds and other risk factors. Design A prospective cohort study. Setting A health survey of the Nord-Trondelag county of Norway. Participants A sample of the general adult population (n=49 948). Primary outcome measure The primary outcome measure is bothersome tinnitus. Results Occupation had a marked effect on tinnitus prevalence. The effect of occupation on tinnitus was reduced in men by controlling for self-reported occupational noise exposure and in women by controlling for education and income. Adding hearing loss as a predictor increased the effect of occupation somewhat. In men, age-adjusted prevalence ratios of tinnitus ranged from 1.5 (workshop mechanics) to 2.1 (crane and hoist operators) in the 10 occupations with highest tinnitus prevalence. In women, the most important contribution to the tinnitus prevalence was from the large group of occupationally inactive persons, with a prevalence ratio of 1.5. Conclusion This study found a moderate association between occupation and bothersome tinnitus.  
  Address Norwegian Institute of Public Health, Division of Mental Health, Oslo, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2044-6055 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:22267709; PMC3269045 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1522  
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Author (up) Kvestad, E.; Czajkowski, N.; Krog, N.H.; Engdahl, B.; Tambs, K. url  doi
  Title Heritability of hearing loss Type Journal Article
  Year 2012 Publication Epidemiology (Cambridge, Mass.) Abbreviated Journal Epidemiology  
  Volume 23 Issue 2 Pages 328-331  
  Keywords Adult; Age Factors; Aged; Aged, 80 and over; Audiometry; Auditory Threshold; Female; Gene-Environment Interaction; Genetic Predisposition to Disease/epidemiology; Hearing Loss/epidemiology/etiology/*genetics; Humans; Male; Middle Aged; Norway/epidemiology; Sex Factors; Young Adult  
  Abstract BACKGROUND: Hearing impairment is one of the most common permanent disabilities in the western world. Although hearing ability normally declines with age, there is great individual variation in age of onset, progression, and severity, indicating that individual susceptibility plays a role. The aim of the present study was to explore the relative importance of genetic and environmental effects in the etiology of impaired hearing. METHODS: From August 1995 to June 1997, the total adult population of Nord-Trondelag County, Norway, was invited to take part in the Nord-Trondelag Health Study. The survey included as an integrated project the Nord-Trondelag Hearing Loss Study with pure-tone audiometry assessment of the standard frequencies 0.25, 0.5, 1, 2, 3, 4, 6, and 8 kHz on 51,574 participants aged 20 to 101 years. We obtained information from Statistics Norway identifying 11,263 sibling pairs. After age stratification, we assessed similarity in hearing thresholds between siblings using polychoric correlations. The contribution of genetic effects in hearing ability was calculated. RESULTS: The upper limit of the heritability of hearing loss was 0.36. We found little evidence for sex differences in the relative importance of genetic effects. CONCLUSIONS: There is a substantial genetic contribution to individual variation in hearing thresholds.  
  Address Division of Mental Health, Norwegian Institute of Public Health, Oslo, Norway. ellen.kvestad@fhi.no  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1044-3983 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:22249243 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1538  
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