toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
  Record Links
Author Mai, X.-M.; Chen, Y.; Camargo, C.A.J.; Langhammer, A. url  doi
  Title Cross-sectional and prospective cohort study of serum 25-hydroxyvitamin D level and obesity in adults: the HUNT study Type Journal Article
  Year 2012 Publication American Journal of Epidemiology Abbreviated Journal Am J Epidemiol  
  Volume 175 Issue 10 Pages 1029-1036  
  Keywords Adult; Biological Markers/blood; Body Mass Index; Cross-Sectional Studies; Female; Follow-Up Studies; Health Surveys; Humans; Hydroxycholecalciferols/blood/*deficiency; Incidence; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Norway/epidemiology; Obesity/blood/epidemiology/*etiology; Odds Ratio; Prevalence; Prospective Studies; Vitamin D Deficiency/blood/*complications; Waist Circumference  
  Abstract Experimental studies suggest that vitamin D modulates the activity of adipocytes. The authors examined baseline serum 25-hydroxyvitamin D (25(OH)D) level in relation to prevalent and cumulative incident obesity in Norway. A cohort of 25,616 adults aged 19-55 years participated in both the second and third surveys of the Nord-Trondelag Health Study (HUNT 2 (1995-1997) and HUNT 3 (2006-2008)). Serum 25(OH)D levels measured at baseline and anthropometric measurements taken at both baseline and follow-up were available for a random sample of 2,460 subjects. Overall, 40% of the 2,460 subjects had a serum 25(OH)D level less than 50.0 nmol/L, and 37% had a level of 50.0-74.9 nmol/L. The prevalence and cumulative incidence of obesity, defined as body mass index (weight (kg)/height (m)(2)) >/=30, were 12% and 15%, respectively. Lower serum 25(OH)D level was associated with a higher prevalence of obesity. In the 2,165 subjects with baseline BMI less than 30, a serum 25(OH)D level less than 50.0 nmol/L was associated with a significantly increased odds ratio for incident obesity during follow-up (adjusted odds ratio = 1.73, 95% confidence interval: 1.24, 2.41). When prevalent and incident obesity were classified according to waist circumference (>/=88 cm for women, >/=102 cm for men), similar results were obtained. In addition to prevalent obesity, a serum 25(OH)D level less than 50.0 nmol/L was significantly associated with new-onset obesity in adults.  
  Address Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway.  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0002-9262 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:22312120 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1551  
Permanent link to this record
Select All    Deselect All
 |   | 

Save Citations:
Export Records: