toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
   print
  Records Links
Author Larose, T.L.; Brumpton, B.M.; Langhammer, A.; Camargo, C.A.J.; Chen, Y.; Romundstad, P.; Mai, X.M.   
  Title Serum 25-hydroxyvitamin D level, smoking and lung function in adults: the HUNT Study Type Journal Article
  Year 2015 Publication Eur Respir J Abbreviated Journal The European respiratory journal  
  Volume 46 Issue 2 Pages 355-363  
  Keywords Adult; Cross-Sectional Studies; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Norway/epidemiology; Odds Ratio; Smoking/*blood/*epidemiology; Spirometry; Vitamin D/*analogs & derivatives/blood; Young Adult  
  Abstract The association between serum 25-hydroxyvitamin D (25(OH)D) level and lung function changes in the general population remains unclear.We conducted cross-sectional (n=1220) and follow-up (n=869) studies to investigate the interrelationship of serum 25(OH)D, smoking and lung function changes in a random sample of adults from the Nord-Trondelag Health (HUNT) Study, Norway.Lung function was measured using spirometry and included forced expiratory volume in 1 s (FEV1) % predicted, forced vital capacity (FVC) % pred and FEV1/FVC ratio. Multiple linear and logistic regression models estimated the adjusted difference in lung function measures or lung function decline, adjusted odds ratios for impaired lung function or development of impaired lung function and 95% confidence intervals.40% of adults had serum 25(OH)D levels  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Scien Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number HUNT @ maria.stuifbergen @ Larose2015b Serial 1837  
Permanent link to this record
 

 
Author Mai, X.-M.; Langhammer, A.; Camargo, C.A.J.; Chen, Y. url  doi
  Title Serum 25-hydroxyvitamin D levels and incident asthma in adults: the HUNT Study Type Journal Article
  Year 2012 Publication American Journal of Epidemiology Abbreviated Journal Am J Epidemiol  
  Volume 176 Issue 12 Pages 1169-1176  
  Keywords Adult; Asthma/*epidemiology; Case-Control Studies; Female; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Norway/epidemiology; Prospective Studies; Rhinitis, Allergic, Perennial/epidemiology; Risk Factors; Sex Distribution; Vitamin D/*analogs & derivatives/blood; Vitamin D Deficiency/*epidemiology  
  Abstract The impact of low vitamin D status on asthma development is unclear. The authors investigated the relation between the baseline serum 25-hydroxyvitamin D (25(OH)D) level and incident asthma in adults, including possible effect modification by allergy status, using allergic rhinitis as a proxy measure. A cohort of 25,616 Norwegian adults aged 19-55 years participated in 2 surveys of the Nord-Trondelag Health Study known as HUNT 2 (1995-1997) and HUNT 3 (2006-2008). Of this cohort, a nested case-control study included 584 new-onset asthma cases and 1,958 nonasthma controls whose baseline serum 25(OH)D levels were measured. After adjustment for potential asthma risk factors, the baseline serum level of 25(OH)D (<50 nmol/L) was not significantly associated with asthma in either women (adjusted odds ratio = 0.94, 95% confidence interval (CI): 0.67, 1.32) or men (adjusted odds ratio = 1.47, 95% CI: 0.93, 2.32). In men, allergic rhinitis modified the association with the adjusted odds ratio being 0.87 (95% CI: 0.36, 2.06) among men with allergic rhinitis and 2.32 (95% CI: 1.06, 5.10) among men without allergic rhinitis. The serum 25(OH)D level was not associated with incident asthma in women, regardless of allergy status. Low vitamin D status was not significantly associated with incident asthma in most adults, but it may have increased risk among men without allergy.  
  Address Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway. xiao-mei.mai@ntnu.no  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0002-9262 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:23204497 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1552  
Permanent link to this record
 

 
Author Sun, Y.-Q.; Langhammer, A.; Wu, C.; Skorpen, F.; Chen, Y.; Nilsen, T.I.L.; Romundstad, P.R.; Mai, X.-M. url  doi
  Title Associations of serum 25-hydroxyvitamin D level with incidence of lung cancer and histologic types in Norwegian adults: a case-cohort analysis of the HUNT study Type Journal Article
  Year 2018 Publication European Journal of Epidemiology Abbreviated Journal Eur J Epidemiol  
  Volume 33 Issue 1 Pages 67-77  
  Keywords Adenocarcinoma/blood/*epidemiology/pathology; Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Incidence; Lung Neoplasms/blood/*epidemiology/pathology; Male; Middle Aged; Norway/epidemiology; Prospective Studies; Vitamin D/*analogs & derivatives/blood; *Case-cohort study; *Histologic types; *Lung cancer; *Pulmonary adenocarcinoma; *Serum 25-hydroxyvitamin D [25(OH)D]; *Vitamin D  
  Abstract Previous prospective studies have shown inconsistent associations between serum 25-hydroxyvitamin D [25(OH)D] level and lung cancer incidence. The aim of the present study was to explore the associations of serum 25(OH)D levels with incidence of lung cancer overall and different histologic types. We performed a population-based prospective case-cohort study including 696 incident lung cancer cases and 5804 individuals in a subcohort who participated in the second survey of the Nord-Trondelag Health Study in Norway. Cox proportional hazards regression models counting for the case-cohort design were used to estimate hazard ratios (HRs) with 95% confidence interval (CIs) for lung cancer overall or histologic types in relation to serum 25(OH)D levels. Compared with the fourth season-specific quartile of 25(OH)D (median 68.0 nmol/L), lower 25(OH)D levels were not associated with the incidence of overall, small or squamous cell lung cancer. However, the risk of adenocarcinoma was lower in the second and third quartiles (median 39.9 and 51.5 nmol/L) compared with the fourth quartile, with HRs of 0.63 (95% CI 0.41-0.98) and 0.58 (0.38-0.88), respectively. The associations of lower levels of 25(OH)D with a reduced risk of adenocarcinoma were only observed in the overweight/obese subjects [HRs for second and third quartiles: 0.40 (0.22-0.72) and 0.50 (0.27-0.92)] but not in the normal weight subjects [HRs: 0.95 (0.52-1.75) and 0.60 (0.32-1.10)]. Serum 25(OH)D levels were not associated with the risk of lung cancer in general. The observation that lower 25(OH)D levels were associated with a lower risk of adenocarcinoma should be interpreted with caution.  
  Address Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0393-2990 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:29080012 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 2178  
Permanent link to this record
Select All    Deselect All
 |   | 
Details
   print

Save Citations:
Export Records: