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Author  |
Natland Fagerhaug, T.; Forsmo, S.; Jacobsen, G.W.; Midthjell, K.; Andersen, L.F.; Ivar Lund Nilsen, T. |

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Title |
A prospective population-based cohort study of lactation and cardiovascular disease mortality: the HUNT study |
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Journal Article |
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Year |
2013 |
Publication |
BMC Public Health |
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BMC Public Health |
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13 |
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1070 |
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Abstract |
BACKGROUND: Recent studies suggest that lactation has long-term effects on risk for cardiovascular disease in women, but the effects on cardiovascular mortality are less well known. METHOD: In a Norwegian population-based prospective cohort study, we studied the association of lifetime duration of lactation with cardiovascular mortality in 21,889 women aged 30 to 85 years who attended the second Nord-Trondelag Health Survey (HUNT2) in 1995-1997. The cohort was followed for mortality through 2010 by a linkage with the Cause of Death Registry. Adjusted hazard ratios (HR) for death from all causes and cardiovascular disease were calculated using Cox regression. RESULTS: During follow-up, 1,246 women died from cardiovascular disease. Parous women younger than 65 years who had never lactated had a higher cardiovascular mortality than the reference group of women who had lactated 24 months or more (HR 2.77, 95% confidence interval [CI]: 1.28, 5.99). There was some evidence of a U-shaped association, where women who reported lactating 7-12 months had a HR of 0.55 (95% CI: 0.27, 1.09). No clear associations were observed among women 65 years or older. CONCLUSIONS: Excess cardiovascular mortality rates were observed among parous women younger than 65 years who had never lactated. These findings support the hypothesis that lactation may have long-term influences on maternal cardiovascular health. |
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Address |
Department of Public Health and General Practice, Norwegian University of Science and Technology, PO Box 8904 MTFS, 7491 Trondheim, Norway. tone.natland.fagerhaug@ntnu.no |
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English |
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1471-2458 |
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Notes |
PMID:24219620; PMC3840666 |
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Call Number |
HUNT @ maria.stuifbergen @ |
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1412 |
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