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Author  |
Brumpton, B.; Langhammer, A.; Romundstad, P.; Chen, Y.; Mai, X.-M. |
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Title |
General and abdominal obesity and incident asthma in adults: the HUNT study |
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Journal Article |
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Year |
2013 |
Publication |
The European Respiratory Journal |
Abbreviated Journal |
Eur Respir J |
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Volume |
41 |
Issue |
2 |
Pages |
323-329 |
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Keywords |
Adult; Asthma/*complications/*epidemiology; Body Mass Index; Female; Humans; Male; Middle Aged; Models, Statistical; Norway; Obesity/*complications/*epidemiology; Odds Ratio; Prospective Studies; Risk Factors; Smoking; Waist Circumference; Young Adult |
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Abstract |
Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom been investigated. To determine the association between BMI, waist circumference and incident asthma in adults, we conducted a prospective study (n=23,245) in a population living in Nord-Trondelag, Norway in 1995-2008. Baseline BMI and waist circumference were measured and categorised as general obesity (BMI >/=30.0 kg.m(2)) and abdominal obesity (waist circumference >/=88 cm in females and >/=102 cm in males). Incident asthma was self-reported new-onset cases during an 11-yr follow-up period. Odds ratios for asthma associated with obesity were calculated using multivariable logistic regression. General obesity was a risk factor for asthma in females (OR 1.96, 95% CI 1.52-2.52) and males (OR 1.84, 95% CI 1.30-2.59). In females, after additional adjustment for BMI, abdominal obesity remained a risk factor for asthma development (OR 1.46, 95% CI 1.04-2.05). Abdominal obesity seems to increase the risk of incident asthma in females in addition to BMI, indicating that using both measures of BMI and waist circumference in females may be a superior clinical assessment for asthma risk than any measure alone. |
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Address |
Dept. of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. ben.brumpton@ntnu.no |
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English |
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Edition |
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ISSN |
0903-1936 |
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Notes |
PMID:22653771 |
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no |
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Call Number |
HUNT @ maria.stuifbergen @ |
Serial |
1461 |
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