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Author (up) Honningsvag, L.-M.; Hagen, K.; Haberg, A.; Stovner, L.J.; Linde, M. url  doi
  Title Intracranial abnormalities and headache: A population-based imaging study (HUNT MRI) Type Journal Article
  Year 2015 Publication Cephalalgia : an International Journal of Headache Abbreviated Journal Cephalalgia  
  Volume Issue Pages  
  Keywords HUNT3; Health survey; cerebral infarction; cysts; malformations; migraine; pathology; tension-type headache; unclassified headache; white matter  
  Abstract BACKGROUND: Most studies on intracranial abnormalities among headache sufferers were performed in selected clinical populations. The aim of this study was to evaluate the relationship between intracranial abnormalities and headache among middle-aged adults in the general population. METHODS: Participants in a large epidemiological study (the HUNT 3 study; 2006-2008) who answered a headache questionnaire and participated in a population-based imaging study of the head (HUNT MRI; 2007-2009) were included (n = 864; age, 50-65 at enrollment). Based on the responses to the HUNT 3 questionnaire, respondents were categorized as having migraine, tension-type headache, or unclassified headache. Logistic regression was used to compare the occurrence of intracranial abnormalities between groups. RESULTS: Intracranial abnormalities were more common in headache sufferers than in headache-free individuals (29% vs. 22%, respectively; p = 0.041). Adjusted multivariate analyses revealed that those with tension-type headache had higher odds of having minor abnormalities (odds ratio, 2.13; 95% confidence interval = 1.18-3.85). This association disappeared when those with only white matter hyperintensities were removed from the analysis. CONCLUSIONS: Headache sufferers had increased odds of minor intracranial abnormalities. The increased odds were primarily related to the presence of white matter hyperintensities.  
  Address Department of Neuroscience, Norwegian University of Science and Technology, Norway Norwegian Advisory Unit on Headache, St. Olavs University Hospital, Norway  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0333-1024 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:25896482 Approved no  
  Call Number HUNT @ maria.stuifbergen @ Serial 1691  
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