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Author (up) Jolle, A.; Midthjell, K.; Holmen, J.; Tuomilehto, J.; Carlsen, S.M.; Shaw, J.; Asvold, B.O. url  doi
  Title Impact of sex and age on the performance of FINDRISC: the HUNT Study in Norway Type Journal Article
  Year 2016 Publication BMJ Open Diabetes Res Care Abbreviated Journal BMJ open diabetes research & care  
  Volume 4 Issue 1 Pages e000217  
  Keywords  
  Abstract OBJECTIVE: The Finnish Diabetes Risk Score (FINDRISC) is recommended as a screening tool for diabetes risk. However, there is a lack of well-powered studies examining the performance of FINDRISC by sex and age. We aim to estimate, by sex and age, the prevalence of elevated FINDRISC and positive predictive value (PPV) of FINDRISC for identifying impaired glucose metabolism (IGM) in a general Norwegian population. RESEARCH DESIGN AND METHODS: We estimated the prevalence of elevated FINDRISC (>/=15) among 47 694 adults in the third survey of the Nord-Trondelag Health Study (HUNT3, 2006-08). Among 2559 participants who participated in oral glucose tolerance testing, we estimated the PPV of elevated FINDRISC for identifying unknown prevalent diabetes and other forms of IGM. RESULTS: The prevalence of elevated FINDRISC was 12.1% in women, 9.6% in men, and increased from 1.5% at age 20-39 to 25.1% at age 70-79 years. The PPVs of elevated FINDRISC were 9.8% for diabetes, 16.9% for impaired glucose tolerance, 8.2% for impaired fasting glucose, and 34.9% for any form of IGM. The PPV for IGM was lower in women (31.2%) than in men (40.4%), and increased from 19.1% at age 20-39 to 55.5% at age >/=80 years. CONCLUSIONS: FINDRISC identified more women than men as high-risk individuals for diabetes. FINDRISC had a high PPV for detecting prevalent IGM, and the PPV was higher in men than in women and in the older individuals. Our data indicate that the impact of sex and age on diabetes risk is not fully captured by FINDRISC, and that refinements to it might improve diabetes prediction.  
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  Publisher Place of Publication Faculty of Medicine, Department of Public Health and General Practice , HUNT Research Centre, NTNU, Editor  
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  Notes Jolle, AnneMidthjell, KristianHolmen, JosteinTuomilehto, JaakkoCarlsen, Sven MShaw, JonathanAsvold, Bjorn OengEngland2016/07/13 06:00BMJ Open Diabetes Res Care. 2016 Jun 22;4(1):e000217. doi: 10.1136/bmjdrc-2016-000217. eCollection 2016. Approved no  
  Call Number HUNT @ maria.stuifbergen @ Jolle2016 Serial 1758  
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