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Author (up) Larsen, J.S.; Skaug, E.A.; Wisloff, U.; Ellingsen, O.; Stovner, L.J.; Linde, M.; Hagen, K. url  doi
  Title Migraine and endothelial function: The HUNT3 Study Type Journal Article
  Year 2016 Publication Cephalalgia Abbreviated Journal Cephalalgia  
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  Abstract BACKGROUND: Reduced endothelial function is associated with elevated risk of cardiovascular disease, but evidence on the association between migraine and endothelial function is conflicting. The aim of this population-based study was to examine the relationship between flow-mediated dilatation (FMD) and migraine with aura, migraine without aura and tension-type headache. METHODS: In the third Nord-Trondelag Healthy Study (HUNT3) FMD was measured by ultrasound during reactive hyperaemia of the brachial artery in a sample of 4739 healthy adult participants, 3929 of whom answered headache questions. The cross-sectional association between different headache diagnoses and FMD was evaluated by logistic regression, using a categorical approach. RESULTS: Mean FMD did not differ between the headache groups and headache-free controls. In multi-adjusted analyses, no consistent association was found between FMD quintiles and headache groups. CONCLUSIONS: There was no relationship between FMD and migraine or other headache diagnoses in this large cross-sectional study of otherwise healthy respondents including freedom from pulmonary and cardiovascular diseases.  
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  Publisher Place of Publication Department of Neuroscience, Norwegian University of Science and Technology, Norway.K.G. Jebsen Cente Editor  
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  Notes Larsen, Joakim SchjolbergSkaug, Eli-AnneWisloff, UlrikEllingsen, OyvindStovner, Lars JacobLinde, MattiasHagen, KnutENG2016/02/13 06:00Cephalalgia. 2016 Feb 10. pii: 0333102416631961. Approved no  
  Call Number HUNT @ maria.stuifbergen @ Larsen2016 Serial 1761  
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