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Author (up) Lier, R.; Mork, P.J.; Holtermann, A.; Nilsen, T.I. url  doi
  Title Familial Risk of Chronic Musculoskeletal Pain and the Importance of Physical Activity and Body Mass Index: Prospective Data from the HUNT Study, Norway Type Journal Article
  Year 2016 Publication PLoS One Abbreviated Journal PloS one  
  Volume 11 Issue 4 Pages e0153828  
  Keywords  
  Abstract The main objectives of the current study was i) to prospectively examine if chronic musculoskeletal pain in parents is associated with risk of chronic musculoskeletal pain in their adult offspring, and ii) to assess if these parent-offspring associations are modified by offspring body mass index and leisure time physical activity. We used data on 4,742 adult offspring linked with their parents who participated in the population-based HUNT Study in Norway in 1995-97 and in 2006-08. Family relations were established through the national Family Registry. A Poisson regression model was used to estimate relative risk (RR) with 95% confidence interval (CI). In total, 1,674 offspring (35.3%) developed chronic musculoskeletal pain during the follow-up period of approximately 11 years. Both maternal (RR: 1.26, 95% CI: 1.03, 1.55) and paternal chronic musculoskeletal pain (RR: 1.29, 95% CI: 1.06, 1.57) was associated with increased risk of offspring chronic musculoskeletal pain. Compared to offspring of parents without chronic musculoskeletal pain, the adverse effect of parental pain was somewhat stronger among offspring who reported a low (RR: 1.82, 95% CI: 1.32, 2.52) versus high (RR: 1.32, 95% CI: 0.95, 1.84) level of leisure time physical activity. Offspring of parents with chronic musculoskeletal pain and who were classified as obese had more than twofold increased risk (RR: 2.33, 95% CI: 1.68, 3.24) of chronic musculoskeletal pain compared to normal weight offspring of parents without pain. In conclusion, parental chronic musculoskeletal pain is positively associated with risk of chronic musculoskeletal pain in their adult offspring. Maintenance of normal body weight may reduce the risk of chronic musculoskeletal pain in offspring of pain-afflicted parents.  
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  Publisher Place of Publication Department of Public Health and General Practice, Norwegian University of Science and Technology, Tr Editor  
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  Notes Lier, RagnhildMork, Paul JarleHoltermann, AndreasNilsen, Tom Ivar Lundeng2016/04/16 06:00PLoS One. 2016 Apr 15;11(4):e0153828. doi: 10.1371/journal.pone.0153828. eCollection 2016. Approved no  
  Call Number HUNT @ maria.stuifbergen @ Lier2016 Serial 1765  
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