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Author (up) Iversen, M.M.; Tell, G.S.; Espehaug, B.; Midthjell, K.; Graue, M.; Rokne, B.; Berge, L.I.; Ostbye, T.
Title Is depression a risk factor for diabetic foot ulcers?: 11-years follow-up of the Nord-Trondelag Health Study (HUNT) Type Journal Article
Year 2015 Publication J Diabetes Complications Abbreviated Journal Journal of diabetes and its complications
Volume 29 Issue 1 Pages 20-25
Keywords HUNT2; HUNT3; Age Distribution; Cohort Studies; Confidence Intervals; Depression/diagnosis/*epidemiology; Diabetic Foot/*epidemiology/physiopathology/*psychology/therapy; Female; Follow-Up Studies; Humans; Incidence; Logistic Models; Longitudinal Studies; Male; Neuropsychological Tests; Norway; Odds Ratio; *Quality of Life; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Distribution; Time Factors; Wound Healing/physiology
Abstract AIM: To prospectively examine whether depressive symptoms increase the risk of diabetes and a diabetic foot ulcer. METHODS: The Nord-Trondelag Health Study (HUNT) is a community-based longitudinal study. The Hospital Anxiety and Depression Scale (HADS-D subscale) assessed depressive symptoms. We followed individuals with complete HADS-D data from HUNT2 (1995-97) and assessed whether they reported diabetes with or without a history of diabetic foot ulcer (DFU) in HUNT3 (2006-08) (n=36,031). Logistic regression was used to investigate the effect of depressive symptoms on subsequent development of diabetes and of DFU. RESULTS: Unadjusted odds for reporting diabetes at follow-up was higher among individuals who reported a HADS-D score>/=8 at baseline (OR 1.30 95% CI, 1.07-1.57) than among those reporting a lower score. After adjusting for age, gender and BMI, this association was no longer significant. The odds of developing a DFU was almost two-fold (OR=1.95 95% CI, 1.02-3.74) for those reporting a HADS-D score of 8-10, and 3-fold (OR=3.06 95% CI, 1.24-7.54) for HADS-D scores>/=11, compared to HADS-D scores
Corporate Author Thesis
Publisher Place of Publication Faculty of Health and Social Sciences, Bergen University College, PO Box 7030, N-5020 Bergen, Norway Editor
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Call Number HUNT @ maria.stuifbergen @ Iversen2015c Serial 1826
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