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Author (up) Straete Rottereng, A.K.; Bosnes, O.; Stordal, E.; Zwart, J.A.; Linde, M.; Stovner, L.J.; Hagen, K. url  doi
  Title Headache as a predictor for dementia: The HUNT Study Type Journal Article
  Year 2015 Publication J Headache Pain Abbreviated Journal The journal of headache and pain  
  Volume 16 Issue 1 Pages 89  
  Keywords HUNT2; HUNT3; Aged; Aged, 80 and over; Dementia/*diagnosis/*epidemiology; Female; Headache/*diagnosis/*epidemiology; Health Surveys/*methods; Humans; Longitudinal Studies; Male; Middle Aged; Migraine Disorders/diagnosis/epidemiology; Norway/epidemiology; Population Surveillance/*methods; Predictive Value of Tests  
  Abstract BACKGROUND: The impact of headache on dementia is largely unknown. This study examined the association between headache and dementia using data from a large population-based study. METHODS: This population-based study used data from the Nord-Trondelag Health Surveys performed in 1995-1997 (HUNT2) and 2006-2008 (HUNT3). The reference group (controls) was participants aged >/=55 years who answered the headache questions in HUNT2 and later participated in HUNT3 (n = 15,601). The association with headache status in HUNT2 was investigated in sample of confirmed non-demented elderly evaluated with psychometric tests after HUNT3 (n = 96), and HUNT2 participants later diagnosed with dementia during 1997-2011 (n = 746). The association with headache was evaluated by logistical regression with adjustment for age, gender, level of education, comorbidity, smoking, and anxiety and depression. RESULTS: Any headache was more likely to be reported in HUNT2 among those who later were included in the dementia registry (OR 1.24; 95 % CI 1.04-1.49) compared to the reference group, but less likely among the confirmed non-demented individuals (OR 0.62; 95 % CI 0.39-0.98). This relationship was even stronger for non-migrainous headache, whereas such association was not found for migraine. CONCLUSIONS: Compared to the reference group, individuals with dementia were more likely to report non-previous migrainous headache in HUNT2, whereas a sample of confirmed non-demented were less likely to report previous non-migrainous headache.  
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  Publisher Place of Publication Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.Depart Editor  
  Language Summary Language Original Title  
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  Series Volume Series Issue Edition  
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  Area Expedition Conference  
  Notes Rottereng, Ane Karoline StraeteBosnes, OleStordal, EysteinZwart, John-AnkerLinde, MattiasStovner, Lars JacobHagen, KnutengItaly2015/10/17 06:00J Headache Pain. 2015 Dec;16(1):89. doi: 10.1186/s10194-015-0573-x. Epub 2015 Oct 15. Approved no  
  Call Number HUNT @ maria.stuifbergen @ StraeteRottereng2015 Serial 1864  
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