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Author (up) Tang, C.S.; Zhang, H.; Cheung, C.Y.; Xu, M.; Ho, J.C.; Zhou, W.; Cherny, S.S.; Zhang, Y.; Holmen, O.; Au, K.W.; Yu, H.; Xu, L.; Jia, J.; Porsch, R.M.; Sun, L.; Xu, W.; Zheng, H.; Wong, L.Y.; Mu, Y.; Dou, J.; Fong, C.H.; Wang, S.; Hong, X.; Dong, L.; Liao, Y.; Wang, J.; Lam, L.S.; Su, X.; Yan, H.; Yang, M.L.; Chen, J.; Siu, C.W.; Xie, G.; Woo, Y.C.; Wu, Y.; Tan, K.C.; Hveem, K.; Cheung, B.M.; Zollner, S.; Xu, A.; Eugene Chen, Y.; Jiang, C.Q.; Lam, T.H.; Ganesh, S.K.; Huo, Y.; Sham, P.C.; Lam, K.S.; Willer, C.J.; Tse, H.F.; Gao, W.   
  Title Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese Type Journal Article
  Year 2015 Publication Nat Commun Abbreviated Journal Nature communications  
  Volume 6 Issue Pages 10206  
  Keywords Asian Continental Ancestry Group/*genetics; Cholesterol, HDL/metabolism; Cholesterol, LDL/metabolism; Exome/*genetics; *Genetic Variation; Genotype; Humans; Lipid Metabolism/*genetics; Triglycerides/metabolism  
  Abstract Blood lipids are important risk factors for coronary artery disease (CAD). Here we perform an exome-wide association study by genotyping 12,685 Chinese, using a custom Illumina HumanExome BeadChip, to identify additional loci influencing lipid levels. Single-variant association analysis on 65,671 single nucleotide polymorphisms reveals 19 loci associated with lipids at exome-wide significance (P  
  Corporate Author Thesis  
  Publisher Place of Publication Department of Psychiatry, the University of Hong Kong, Hong Kong, China.Department of Internal Medic Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
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  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number HUNT @ maria.stuifbergen @ Tang2015 Serial 1866  
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