%0 Journal Article
%T A prospective population-based cohort study of lactation and cardiovascular disease mortality: the HUNT study
%A Natland Fagerhaug, T.
%A Forsmo, S.
%A Jacobsen, G. W.
%A Midthjell, K.
%A Andersen, L. F.
%A Ivar Lund Nilsen, T.
%J BMC Public Health
%D 2013
%V 13
%@ 1471-2458
%G English
%F NatlandFagerhaug_etal2013
%O PMID:24219620; PMC3840666
%O exported from refbase (http://vev.medisin.ntnu.no/refbase/show.php?record=1412), last updated on Thu, 13 Feb 2014 14:18:46 +0100
%X BACKGROUND: Recent studies suggest that lactation has long-term effects on risk for cardiovascular disease in women, but the effects on cardiovascular mortality are less well known. METHOD: In a Norwegian population-based prospective cohort study, we studied the association of lifetime duration of lactation with cardiovascular mortality in 21,889 women aged 30 to 85 years who attended the second Nord-Trondelag Health Survey (HUNT2) in 1995-1997. The cohort was followed for mortality through 2010 by a linkage with the Cause of Death Registry. Adjusted hazard ratios (HR) for death from all causes and cardiovascular disease were calculated using Cox regression. RESULTS: During follow-up, 1,246 women died from cardiovascular disease. Parous women younger than 65 years who had never lactated had a higher cardiovascular mortality than the reference group of women who had lactated 24 months or more (HR 2.77, 95% confidence interval [CI]: 1.28, 5.99). There was some evidence of a U-shaped association, where women who reported lactating 7-12 months had a HR of 0.55 (95% CI: 0.27, 1.09). No clear associations were observed among women 65 years or older. CONCLUSIONS: Excess cardiovascular mortality rates were observed among parous women younger than 65 years who had never lactated. These findings support the hypothesis that lactation may have long-term influences on maternal cardiovascular health.
%R 10.1186/1471-2458-13-1070
%U http://www.ncbi.nlm.nih.gov/pubmed/24219620
%U https://doi.org/10.1186/1471-2458-13-1070
%P 1070