@Article{Gudmundsdottir_etal2013, author="Gudmundsdottir, S. L. and Flanders, W. D. and Augestad, L. B.", title="Physical activity and age at menopause: the Nord-Trondelag population-based health study", journal="Climacteric : the Journal of the International Menopause Society", year="2013", volume="16", number="1", pages="78--87", optkeywords="Adult; Age Factors; Confidence Intervals; Female; Health Surveys; Humans; Kaplan-Meier Estimate; Logistic Models; *Menopause; Middle Aged; Motor Activity/*physiology; Norway; Odds Ratio; Proportional Hazards Models; Young Adult", abstract="BACKGROUND: Age at menopause may affect women{\textquoteright}s subsequent morbidity and mortality. In contrast to numerous other health outcomes, little is known about the possible effects of physical activity on age at menopause. OBJECTIVES: To assess the relationship between leisure-time physical activity and age at menopause. METHODS: Premenopausal women participating in a population-based health survey (HUNT 2) conducted in the county of Nord-Trondelag, Norway reported their physical activity in the period of 1995-1997. Age at menopause was reported during 2006-2008 (HUNT 3). Cox proportional hazards models were used to estimate hazard ratios for menopause and logistic regression to estimate odds ratios for early menopause, with 95{\%} confidence intervals, adjusting for age at menarche, parity, use of oral contraceptives prior to the 6 months preceding participation in HUNT 2, symptoms of depression, smoking status, and education. RESULTS: Women aged 40-49 years at baseline had lower hazard ratios for menopause when participating in any light leisure-time physical activity compared with no activity (p < 0.05) and similar results were observed in 19-39-year-olds. In 50-59-year-old women, the results varied greatly and did not reach statistical significance. CONCLUSIONS: The effects of leisure-time physical activity on age at menopause may be age-dependent. We found indications of earlier menopause for the least active women aged 19-49 years at baseline.", optnote="PMID:22339441", optnote="exported from refbase (http://vev.medisin.ntnu.no/refbase/show.php?record=1449), last updated on Thu, 13 Feb 2014 22:02:09 +0100", issn="1369-7137", doi="10.3109/13697137.2011.646344", opturl="http://www.ncbi.nlm.nih.gov/pubmed/22339441", opturl="https://doi.org/10.3109/13697137.2011.646344", language="English" }