@Article{Brumpton_etal2013, author="Brumpton, B. and Langhammer, A. and Romundstad, P. and Chen, Y. and Mai, X-M", title="General and abdominal obesity and incident asthma in adults: the HUNT study", journal="The European Respiratory Journal", year="2013", volume="41", number="2", pages="323--329", optkeywords="Adult; Asthma/*complications/*epidemiology; Body Mass Index; Female; Humans; Male; Middle Aged; Models; Statistical; Norway; Obesity/*complications/*epidemiology; Odds Ratio; Prospective Studies; Risk Factors; Smoking; Waist Circumference; Young Adult", abstract="Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom been investigated. To determine the association between BMI, waist circumference and incident asthma in adults, we conducted a prospective study (n=23,245) in a population living in Nord-Trondelag, Norway in 1995-2008. Baseline BMI and waist circumference were measured and categorised as general obesity (BMI >/=30.0 kg.m(2)) and abdominal obesity (waist circumference >/=88 cm in females and >/=102 cm in males). Incident asthma was self-reported new-onset cases during an 11-yr follow-up period. Odds ratios for asthma associated with obesity were calculated using multivariable logistic regression. General obesity was a risk factor for asthma in females (OR 1.96, 95{\%} CI 1.52-2.52) and males (OR 1.84, 95{\%} CI 1.30-2.59). In females, after additional adjustment for BMI, abdominal obesity remained a risk factor for asthma development (OR 1.46, 95{\%} CI 1.04-2.05). Abdominal obesity seems to increase the risk of incident asthma in females in addition to BMI, indicating that using both measures of BMI and waist circumference in females may be a superior clinical assessment for asthma risk than any measure alone.", optnote="PMID:22653771", optnote="exported from refbase (http://vev.medisin.ntnu.no/refbase/show.php?record=1461), last updated on Thu, 13 Feb 2014 22:06:16 +0100", issn="0903-1936", doi="10.1183/09031936.00012112", opturl="http://www.ncbi.nlm.nih.gov/pubmed/22653771", opturl="https://doi.org/10.1183/09031936.00012112", language="English" }