%0 Journal Article
%T Is depression a risk factor for diabetic foot ulcers?: 11-years follow-up of the Nord-Trondelag Health Study (HUNT)
%A Iversen, M. M.
%A Tell, G. S.
%A Espehaug, B.
%A Midthjell, K.
%A Graue, M.
%A Rokne, B.
%A Berge, L. I.
%A Ostbye, T.
%J J Diabetes Complications
%D 2015
%V 29
%N 1
%C Faculty of Health and Social Sciences, Bergen University College, PO Box 7030, N-5020 Bergen, Norway
%F Iversen_etal2015
%O exported from refbase (http://vev.medisin.ntnu.no/refbase/show.php?record=1826), last updated on Thu, 11 Aug 2016 12:42:25 +0200
%X AIM: To prospectively examine whether depressive symptoms increase the risk of diabetes and a diabetic foot ulcer. METHODS: The Nord-Trondelag Health Study (HUNT) is a community-based longitudinal study. The Hospital Anxiety and Depression Scale (HADS-D subscale) assessed depressive symptoms. We followed individuals with complete HADS-D data from HUNT2 (1995-97) and assessed whether they reported diabetes with or without a history of diabetic foot ulcer (DFU) in HUNT3 (2006-08) (n=36,031). Logistic regression was used to investigate the effect of depressive symptoms on subsequent development of diabetes and of DFU. RESULTS: Unadjusted odds for reporting diabetes at follow-up was higher among individuals who reported a HADS-D score>/=8 at baseline (OR 1.30 95% CI, 1.07-1.57) than among those reporting a lower score. After adjusting for age, gender and BMI, this association was no longer significant. The odds of developing a DFU was almost two-fold (OR=1.95 95% CI, 1.02-3.74) for those reporting a HADS-D score of 8-10, and 3-fold (OR=3.06 95% CI, 1.24-7.54) for HADS-D scores>/=11, compared to HADS-D scores
%K HUNT2
%K HUNT3
%K Age Distribution
%K Cohort Studies
%K Confidence Intervals
%K Depression/diagnosis/*epidemiology
%K Diabetic Foot/*epidemiology/physiopathology/*psychology/therapy
%K Female
%K Follow-Up Studies
%K Humans
%K Incidence
%K Logistic Models
%K Longitudinal Studies
%K Male
%K Neuropsychological Tests
%K Norway
%K Odds Ratio
%K *Quality of Life
%K Retrospective Studies
%K Risk Assessment
%K Severity of Illness Index
%K Sex Distribution
%K Time Factors
%K Wound Healing/physiology
%P 20-25