@Article{Gulati_etal2017,
author="Gulati, A. M.
and Hoff, M.
and Salvesen, O.
and Dhainaut, A.
and Semb, A. G.
and Kavanaugh, A.
and Haugeberg, G.",
title="Bone mineral density in patients with psoriatic arthritis: data from the Nord-Trondelag Health Study 3",
journal="RMD Open",
year="2017",
volume="3",
number="1",
pages="e000413",
optkeywords="Psoriatic arthritis; bone mineral density; osteoporosis",
abstract="BACKGROUND: The risk of osteoporosis in patients with psoriatic arthritis (PsA) remains unclear. The aim of this study was to compare bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) in patients with PsA and controls. PATIENTS AND METHODS: Patients with PsA and controls were recruited from the Nord-Trondelag Health Study (HUNT) 3. RESULTS: Patients with PsA (n=69) and controls (n=11 703) were comparable in terms of age (56.8 vs 55.3 years, p=0.32), gender distribution (females 65.2{\%} vs 64.3{\%}, p=0.87) and postmenopausal status (75.6{\%} vs 62.8{\%}, p=0.08). Body mass index (BMI) was higher in patients with PsA compared with controls (28.5 vs 27.2 kg/m(2), p=0.01). After adjusting for potential confounding factors (including BMI), BMD was higher in patients with PsA compared with controls at lumbar spine 1-4 (1.213 vs 1.147 g/cm(2), p=0.003) and femoral neck (0.960 vs 0.926 g/cm(2), p=0.02), but not at total hip (1.013 vs 0.982 g/cm(2), p=0.11). Controls had significantly higher odds of having osteopenia or osteoporosis based on measurements of BMD in both the femoral neck (p=0.001), total hip (p=0.033) and lumbar spine (p=0.033). CONCLUSION: Our population-based data showed comparable BMD in patients with PsA and controls. This supports that the PsA population is not at increased risk of osteoporosis.",
optnote="PMID:28955483; PMCID:PMC5604602",
optnote="exported from refbase (http://vev.medisin.ntnu.no/refbase/show.php?record=1919), last updated on Fri, 02 Feb 2018 16:02:34 +0100",
issn="2056-5933",
doi="10.1136/rmdopen-2016-000413",
opturl="http://www.ncbi.nlm.nih.gov/pubmed/28955483",
opturl="https://doi.org/10.1136/rmdopen-2016-000413",
language="English"
}